Cannabis Once Again Shown To Halt Cancer Growth — So Why Aren’t We Studying It In Humans?

  • by Paul Armentano, NORML Deputy Director August 4, 2010

    [Editor’s note: This post is excerpted from this week’s forthcoming NORML weekly media advisory. To have NORML’s media advisories delivered straight to your in-box, sign up for NORML’s free e-zine here.]

    The administration of THC reduces the tumor growth of metastatic breast cancer and “might constitute a new therapeutic tool for the treatment” of cancerous tumors, according to preclinical data published online in the journal Molecular Cancer.

    Investigators from Complutense University in Madrid assessed the anti-tumor potential of THC and JWH-133, a non-psychotropic CB2 receptor-selective agonist, in the treatment of ErbB2-positive breast tumors – a highly aggressive form of breast cancer that is typically unresponsive to standard therapies.

    Researchers reported, “[B]oth Delta-9-tetrahydrocannabinol … and JWH-133 …reduce tumor growth [and] tumor number [in mice]. … [T]hese results provide a strong preclinical evidence for the use of cannabinoid-based therapies for the management of ErbB2-positive breast cancer.”

    In 2007, investigators at the California Pacific Medical Center Research Institute reported that the administration of the nonpsychoactive cannabinoid CBD limited breast cancer metastasis in a manner that was superior to comparable synthesized agents.

    Previous preclinical studies assessing the anticancer properties of cannabinoids have shown that they inhibit the proliferation of a wide range of cancers, including brain cancer, prostate cancer, oral cancers, lung cancer, skin cancer, pancreatic cancer, biliary tract cancers, and lymphoma.

    Full text of the study, “Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition,” is available online here.

    83 Responses to “Cannabis Once Again Shown To Halt Cancer Growth — So Why Aren’t We Studying It In Humans?”

    1. Mia says:

      My pit bull was diagnosed with osteosarcoma I have taken the huge step to amputate her leg but I can’t afford chemotherapy so I am trying the highly recommended hemp oil. She is 85lbs n I wnted to knw wut is the correct dose to give her n how often

    2. Douglas Downey says:

      MSU does not adhere to this medicinal treatment, they did not advise us to try this or even have any comments when we asked them about it, we do not hold that against them, we thank the staff for the great care they provided for the dog while she was there and without their expertise and technology we would never have known there was a mass on her spine or why she was stumbling in the first place…but there are Veterinarians that have published studies on cannabinoid and THC treatments of cancer in dogs and there are some pretty positive results…hope we experience some as well!

    3. Douglas Downey says:

      We decided on Oral ingestion of Simpson Oil as a treatment…consulted a Vet that has experience with alternative treatments such as non psychoactive CBD’s…so for anyone reading this, the dog is not getting high at all, the cannabinoids stop cancer cells from reproducing thus halting tumor growth…this is our targeted result, not getting an animal intoxicated, she is currently prescribed opioid pain relievers and steroids from MSU, that will be the only psychoactive narcotic that is introduced into this beautiful animal who without some type of treatment will soon be paralyzed…This is our last resort to try to improve the quality of what life she does have left and if it helps to prolong her life and that quality of…then I will do everything I can to publish our documentation of this study/life saving effort:) thanks for the info and your support Jimmy!

    Leave a Reply