Even More Science Suggesting That Cannabinoids May Halt Diabetes

  • by Paul Armentano, NORML Deputy Director June 10, 2013

    Preclinical study data published online in the scientific journal Nutrition & Diabetes reports that tetrahydrocannabivarin (THCV) — a naturally occurring analogue of THC — possesses positive metabolic effects in animal models of obesity.

    British researchers assessed the effects of THCV administration on dietary-induced and genetically modified obese mice. Authors reported that although THCV administration did not significantly affect food intake or body weight gain in any of the models, it did produce several metabolically beneficial effects, including reduced glucose intolerance, improved glucose tolerance, improved liver triglyceride levels, and increased insulin sensitivity.

    Researchers concluded: “Based on these data, it can be suggested that THCV may be useful for the treatment of the metabolic syndrome and/or type 2 diabetes (adult onset diabetes), either alone or in combination with existing treatments. Given the reported benefits of another non-THC cannabinoid, CBD in type 1 diabetes, a CBD/THCV combination may be beneficial for different types of diabetes mellitus.”

    Last month, Harvard Medical School researchers published observational data in The American Journal of Medicine reporting that subjects who regularly consume cannabis possess favorable indices related to diabetic control as compared to occasional consumers or non-users of the substance. Writing in an accompanying commentary, the journal’s Editor-in-Chief stated: “These are indeed remarkable observations that are supported, as the authors note, by basic science experiments that came to similar conclusions. … I would like to call on the NIH and the DEA to collaborate in developing policies to implement solid scientific investigations that would lead to information assisting physicians in the proper use and prescription of THC in its synthetic or herbal form.”

    Observational trial data published in 2012 in the British Medical Journal previously reported that adults with a history of marijuana use had a lower prevalence of type 2 diabetes and possess a lower risk of contracting the disease than did those with no history of cannabis consumption, even after researchers adjusted for social variables such as subjects’ ethnicity and levels of physical activity.

    Previously published preclinical data also indicates that the administration of cannabidiol (CBD) halts the development of type 1 (juvenile) diabetes in mice genetically predisposed to the condition.

    Full text of the study, “The cannabinoid ?9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity,” is available online here.

    31 Responses to “Even More Science Suggesting That Cannabinoids May Halt Diabetes”

    1. I remember 10 years ago, the marijuana movement was just picking up steam, and now we have several very credible and professional sources of calm, rational thought on why people deserve to know the truth about a natural plant with so many benefits. Very glad to be alive in these exciting times :-)

    2. Jolly O Toker says:

      Well DUH.. We have been trying to tell you for years that Cannabis does help with many things. You see we were laughed at and frown upon all for using Cannabis ever since 1937. Let me ask you (the government) something, do you honestly believe that we still have the same mindset as in 1937? This is 2013 and we already put a man on the moon. I really think we should be asking our government which mindset are they on, is it 1937 or 2013 ?

      • weaz1 says:

        What you are not understanding is their plan. They don’t want people to survive and so they established organizations (DEA, ATF, FDA, etc) where the heads are not responsible to anyone but the ones who hired them. These heads are convinced or threatened into believing in depopululation and the machine starts to grind forward. The System is working fine, but they have broken society into zombieism.

    3. John Mcclane says:

      Joint conference with President Choom:http://www.youtube.com/watch?v=DkZCXRKIahY

    4. If this is true; I am so thankful. I am in 13 years of diabetes type 2; and being a marijuana smoker; I can honestly say, that smoking it does alleviate my pain from this disease. My son, who was 49 and died from diabetes, did not smoke marijuana. I do, and I am still here; with none of the horrifying side effects that diabetes is capable of. Maybe diabetes should be considered as a legit reason, to smoke marijuana? It is also a very harmless drug, with many good side effects. No wonder it is being accepted by the people; they are tired of lies associated with its use. It is less harmful then alcohol or tobacco, as we all know. Is it possible that those large companies (alcohol and tobacco) are the biggest lobbyists, trying to stop its legalization; fearing their own products of death, may be endangered?

    5. frank says:

      … and the beat goes on and on .. more and more science proving that this flower does more good than anything else … yet these so called political leaders are as OBTUSE as ever … the change we’re hoping for sometimes seems so, so slow! Here in PA … they layoff teachers, take those savings to free funds to build prisons … that’s the OBTUSE I’m talking about.

    6. Miles says:

      One really has to wonder just how much longer the Feds are going to ignore the medical utility of cannabis and decide to change it’s schedule 1 drug status. My guess is it will be when they have somehow managed to ensure that they will profit greatly once they allow it to happen.

    7. Timbo says:

      Type 1 diabetic here, although much different than type 2 diabetes(cause of why the immune system attacks the Islet cells in the pancreas) if this actually works for humans this would be amazing for the young people who would potentially be diagnosed with this curse would save so much heart ache and pain it would be awesome if this could potentially find a cure for type 1 diabetes although I’m not holding my breath on that.

    8. Lincoln says:

      Schedule I substances are those that have the following findings:

      • The drug or other substance has a high potential for abuse.
      • The drug or other substance has no currently accepted medical use in treatment in the United States.
      • There is a lack of accepted safety for use of the drug or other substance under medical supervision.

      This new medical evidence pretty much nullifies these conditions as related to the cannabis plant.

      RESCHEDULE or remove schedule status entirely and treat this plant as we view other botanicals (i.e. Ginseng, Holy Basil, Ashwagandha, Echinacea, etc.)

      Let’s swap, the illegal status of, cannabis for another herb in the plant kingdom that truly is harmful to our health such as POISON IVY!


    9. cj says:

      “Our” Government has Patents on processes using THC for medicinal purposes (some since the 90’s). So,they know about the medicinal properties of cannabis (for Decades)Look up US Patent # 6630507. One of the patents has to do with diabetes,and a process to help control or eliminate the use of insulin in certin cases. Its all just a big “PUPPET SHOW” people and were all paying for it!

    10. sam blue says:

      What can I say? The special interests have a lot to lose financially if cannabis is legalized. They are the most greedy bunch of people on the planet Earth. For them, judgement day cannot come soon enough. They have caused UN-necessary
      suffering for so many people. Lord help us.

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