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Updated And Expanded: NORML’s Emerging Clinical Applications For Cannabis & Cannabinoids

  • by Paul Armentano, NORML Deputy Director September 2, 2015

    NORML is pleased to present the latest expanded/updated edition of the publication Emerging Clinical Applications for Cannabis & Cannabinoids — a comprehensive review of the latest peer-reviewed science specific to the safety and therapeutic efficacy of whole-plant cannabis and/or its components.

    The 2015 updated edition includes two additional disease profiles (Parkinson’s disease and PTS) and includes summaries of an additional 50+ relevant clinical and/or preclinical trials specific to cannabinoids’ therapeutic utility. Several existing sections, such as Chronic Pain, Diabetes, and Epilepsy, have been significantly expanded since the last edition (January 2013). Also updated is the Introduction to the Endocannabinoid System (authored by Dustin Sulak, DO) and Why I Recommend Medical Cannabis (authored by Estelle Goldstein, MD).

    With summaries and citations of well over 250 recent peer-reviewed studies, this updated publication is one of the most thorough and up-to-date source-books available specific to documenting the established therapeutic qualities of cannabis. The updated publication is available online here.

    Individual sections of this publication may be accessed at the links below:

    Author’s Introduction
    Foreword
    Introduction to the Endocannabinoid System
    Why I Recommend Medical Cannabis
    Alzheimer’s Disease
    Amyotrophic Lateral Sclerosis
    Chronic Pain
    Diabetes Mellitus
    Dystonia
    Epilepsy
    Fibromyalgia
    Gastrointestinal Disorders
    Gliomas/Cancer
    Hepatitis C
    Human Immunodeficiency Virus
    Huntington’s Disease
    Hypertension
    Incontinence
    Methicillin-resistant Staphyloccus aureus (MRSA)
    Multiple Sclerosis
    Osteoporosis
    Parkinson’s Disease
    Post-Traumatic Stress
    Pruritus
    Rheumatoid Arthritis
    Sleep Apnea
    Tourette’s Syndrome

    19 Responses to “Updated And Expanded: NORML’s Emerging Clinical Applications For Cannabis & Cannabinoids”

    1. Gweedo says:

      This is so great to see NORML compiling all this information, but I can’t help but feel like it’s missing a lot.

      This seems to cover a lot of major illnesses which don’t have any other adequate treatment, but it ignores the countless things for which cannabis is simply the most natural (and often most effective) treatment such as menstrual cramps, insomnia, general nausea or headaches….

      Maybe it would be too long to list every little thing for which cannabis has been shown to be an effective treatment, but it would be nice some day to have a complete (and continually updated) list of every potential medicinal benefit of cannabis.

      But regardless of this, my thanks to Paul and whomever else was involved in putting this publication together. This will be a great resource for the community overall.

    2. Anonymous says:

      Sorry, but that’s just not “enough” “known medical use” for marijuana to be removed from Schedule I. (too sarcastic?)

    3. Growyourown says:

      I’d add depression, malaise and glaucoma to Gweedo’s list. Will be glad when everyone realizes the wonderful benefits cannabis can provide in addition to just getting a high.

      [Paul Armentano responds: To clarify, this publication is not meant to be exhaustive. Its focus is specific to recent peer-reviewed science. In cases like nausea the science is well established and dates back decades. In some other cases, like depression, the data is primarily anecdotal.]

    4. brenda says:

      What about neuropathy? My mother has it in her legs pretty bad and cbd oil seems to be making it worse. Why would this be? And she’s also getting cramps in her toes. Any suggestions?

      [Paul Armentano responds: The Chronic Pain section addresses the relevant science specific to cannabinoids and neuropathy.]

    5. Todd says:

      Today is September 3rd. Did the administration respond to “Senators Press Feds for Answers Regarding the State of Medical Marijuana Research” by August 31st?

    6. Julian says:

      Paul, have a hard-cover copy made for the desks of Grassley and Feinstein. Then place a copy of the recent National Geographic “weed” covered over the coffee tables to the entrance of their offices. Then buy them a subscription of The Cannabist to their DC and home offices. Finally, let’s research their family medical history and send them literature on specific treatment from the consumption of marijuana. That oughtta speed up their “Federal inquiries.” :-)

    7. Jane says:

      Lung disease….3rd leading cause of death in the USA. But it looks like people with lung issues can’t be helped by MJ because lung issues are never mentioned in all these long lists of conditions it helps. (rarely you may see asthma mentioned)

      Are there no CBD receptors in the human lung? Is the lung the only part of the body not helped by marijuana?

    8. Mark I. says:

      Prohibition has devastated families, enriched the prison industrial complex, enabled excuse mongering to permit ceasing personal property without due processes, and leaving destitute whole communities victim of policing for profit.

    9. mexweed says:

      @Jane’s lung question is a reminder that by SUBSTITUTING FOR TOBACCO cannabis can PREVENT a monster percentage of lung pathologies, thus whether it helps cure them would be moot, legalization offers decisive benefit.

      (Substitution 2: VAPE NOT BURN.

      Substitution 3: 25-mg World Single Toke Convention, Handmake-It-Yourself Flexdrawtube One-hitter industry to replace obsolete 500-mg Joint and 700-mg $igarette formats.)

    10. vickia52 says:

      Don’t you get it? All the legal shit is killing us! Tobacco, liquor, cigs, sugar, all the food ADDITIVES, fracking, smoke in air, from planes, cars, rockets, trains, factories, pharmaa drugs and on and on. And one little plant, that make 99.9 percent of users happy, non violent, sociable,etc. Think!

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