Inhaling cannabis is associated with the remission of refractory idiopathic angioedema, according to a clinical report published in the journal Case Reports in Immunology. Angioedema is a condition characterized by rapid swelling under the skin in regions around the face and throat, which may result in airway obstruction or suffocation.
Investigators from the Soroka University Medical Center in Israel reported on the progress of a 27-year-old male patient with life-threatening, recurrent angioedema of unknown origin. Doctors placed the patient on a regiment of 20 grams of inhaled cannabis monthly after he failed to respond favorably to prescribed steroids and antihistamines.
Authors reported: “The use of inhaled cannabis resulted in a complete response, and he has been free of symptoms for 2 years. An attempt to withhold the inhaled cannabis led to a recurrent attack within a week, and resuming cannabis maintained the remission, suggesting a cause and effect relationship.”
They concluded: “This is the first report in which a cannabis product for the treatment of refractory idiopathic angioedema was associated with an excellent clinical response. … More research into the exact mechanism of action of cannabis products in cases of idiopathic angioedema and on the modulation of the immune response in general is indicated.”
The Israeli government has authorized the limited production and distribution of marijuana as a medical treatment since 2011, and preparations of the plant are expected to be available in pharmacies imminently.
Full text of the report, “Life threatening idiopathic recurrent angioedema responding to cannabis,” appears online here.
Republican Gov. Bruce Rauner on Friday issued an amendatory veto to House Bill 218, which seeks to decriminalize minor marijuana possession offenses.
As initially approved by the legislature in May, HB 218 reduced personal use possession penalties (up to 15 grams) from a Class A criminal misdemeanor, punishable by up to 6 months in jail, a $1,500 fine, and a criminal record, to a petty offense, punishable by a fine only (up to $125.00) – no arrest, and no criminal record. Governor Rauner’s amendatory veto seeks to decrease the proposed possession limits from 15 grams to 10 grams, whole also seeking to raise fines to $200.00.
Governor Rauner also seeks to lower the state’s proposed per se THC/blood limit from 15ng/ml to 5ng/ml. Under present Illinois law, drivers with any detectable amount of THC in their blood are in violation of the state’s traffic safety laws.
If a majority of lawmakers fail to approve of the Governor’s amendments, the measure will be dead for this year’s legislative session.
To date, 20 states and Washington, DC have passed legislation eliminating the threat of incarceration for marijuana possession offenses via either legalization or decriminalization.
For those of us who have spent years in the trenches of marijuana policy reform, it has been a rare sight to see elected leaders actually lead. It has been the voting public who have paved the way.
But there is a glimmer of hope in Oregon.
In the four states, and the District of Columbia, that have legalized marijuana in the face of federal prohibition, those courageous and innovative steps were taken by the voters, not the elected officials in those jurisdictions.
In fact, not only were most elected officials unwilling to seriously consider enacting legalization legislatively, most also publicly opposed the proposals and urged their defeat at the polls. Fortunately the voters led the way, and left their “leaders” to follow.
So we are accustomed to the challenge of moving progressive marijuana legislation forward despite the active opposition of most politicians. It means we mostly focus on those states that offer a voter initiative as a way to change public policy by going around the legislature. And it sometimes results in constitutional amendments being proposed, despite higher approval requirements in some states, to protect against the possibility that the legislature might simply ignore the will of the voters and reverse a legalization initiative by a vote of the out-of-touch legislators still holding on to their war-on-marijuana mentality.
But there are some new signs that this overwhelming opposition of elected officials to marijuana legalization may be coming to an end, at least in some states, and that some elected officials are now deciding to embrace these new changes and to take steps to implement them in a common-sense manner, to serve the public interest.
I am referring specifically to the recent decision of the Oregon legislature to begin offering legal recreational marijuana sales a year earlier than had been expected. They had no legal requirement to make this change, but they decided to accept the will of the voters and to implement the new law sooner rather than later. They acted like leaders, rather than sore losers.
SB 460 Approved by Legislature, Signed by Governor
Measure 91, the legalization initiative that was approved by 56 percent of Oregon voters in November of 2014, would have been implemented in two-steps. First, as of July 1, 2015, it became legal for those 21 and above to possess up to an ounce of marijuana, to possess up to 8 ounces in the home, and to privately cultivate up to four plants. But provisions in the initiative that gave the Oregon Liquor Control Commission the authority to begin issuing licenses for commercial growers and sellers, delayed this process until January 4, 2016, and legal dispensaries were not expected to be operational until October of 2016.
The result, like the current situation in the District of Columbia, is that recreational marijuana is now legal in Oregon, but there is no legal market. But unlike the District, where the City Council has been hamstrung by Congress in their efforts to establish licensed growers and sellers, the Oregon legislature decided to fix the problem with a short-term solution – they enacted emergency legislation allowing the existing 300-plus licensed medical marijuana dispensaries, which are regulated by the Oregon Health Authority, to begin selling to adult recreational smokers on October 1, 2015.
Recreational consumers will also be able to purchase marijuana seeds and up to four non-flowering plants. (In a nod to local control, counties that opposed Measure 91 with at least 55 percent of the vote, all located on the east side of the state, were given the right to ban recreational sales during this interim program.)
That’s right! The legislature enacted, and Gov. Kate Brown promptly signed, SB 460, bringing full legalization to Oregon a full year ahead of schedule. For once, instead of trying to undermine the new law, they have embraced it and elected to try to make it work as intended by the voters.
Gov. Brown’s office called the measure “a smart solution to a short-term logistical problem,” adding, “If marijuana is legal to use, it shouldn’t be illegal to buy.”
The new law will permit recreational users to purchase up to one-quarter of an ounce of marijuana per transaction from any of the licensed medical dispensaries. The Oregon Liquor Control Commission will continue forward with the process of issuing recreational licenses after the first of the year, and when those new recreational dispensaries are up and running, consumers will be permitted to purchase up to one ounce of marijuana per transaction.
A Model for Elected Officials Moving Forward
One admirable, common sense step by one state legislature does not make a trend, but it does establish a powerful example of how elected officials can get ahead of the curve and work cooperatively to implement these new laws, without delay, and one that can be the model for elected officials in the states that are expected to adopt legalization in the coming months.
A majority of the voters nationwide now support full legalization, and that support appears to be growing. They understand that prohibition is a failed public policy and legalization with regulation is a better option for everyone, smokers and non-smokers alike. When voters clearly register their approval for marijuana legalization, it’s time for the politicians to acknowledge that change, embrace it, and take steps to implement the new laws in a timely and responsible manner. It is time to lead, for a change.
This column first appeared @ marijuana.com.
The Ohio Secretary of State’s office yesterday confirmed that a statewide ballot proposal seeking to permit the personal use and commercial production and retail sale of cannabis will appear on the November ballot. Proponents of the measure, Responsible Ohio, gathered sufficient signatures to place the issue before voters as a constitutional amendment.
Ohio now has the opportunity to join Colorado, Washington, Oregon, Alaska and Washington D.C. as states that have passed laws allowing for the personal possession and consumption of cannabis by adults.
If enacted, the measure would initially establish 10 state-licensed commercial growing sites. (State regulators will have the opportunity to grant additional licenses if these initial production sites do not adequately meet demand.) Commercially produced cannabis will be sold at over 1,000 proposed retail dispensaries.
A minimum of five regional marijuana testing facilities will be established to regularly check the chemical compounds found in the product for adequate labeling for consumers and regulators.
Additionally, residents over the age of 21 will be allowed to purchase a $50 license to grow their own marijuana plants with a limit of 4 plants per household and/or 8 ounces of useable product at a time. The amendment also establishes a non-profit medical marijuana dispensary system to provide access to those patients with a recommendation from a physician. Medical marijuana will not be taxed and will be provided on a needs-based fee system. Commercial marijuana production will be taxed at 5% when purchased for personal use and 15% at the wholesale and manufacturing level.
You can read the full text of the amendment here.
A history of cannabis use is associated with a lower likelihood of obesity and diabetes, according to population-based data published in the journal Obesity.
Investigators from the Conference of Quebec University Health Centers assessed cannabis use patterns and body mass index (BMI) in a cohort of 786 Inuit (Arctic aboriginal) adults ages 18 to 74. Researchers reported that subjects who consumed cannabis in the past year were more likely to possess a lower BMI, lower fasting insulin, and lower HOMA-IR (insulin resistance) as compared to those who did not use the substance.
Specifically, researchers reported that cannabis users possessed an average BMI of 26.8 compared to an index of 28.6 for non-users, after controlling for age, gender and other factors. Those subjects who reported using cannabis but never having used tobacco, or who were former users of tobacco, possessed on average the lowest BMI.
Authors concluded: “In this large cross-sectional adult survey with high prevalence of both substance use and obesity, cannabis use in the past year was associated with lower BMI, lower percentage fat mass, lower fasting insulin, and HOMA-IR. … The inverse association observed in our work supports evidence from a larger proportion of previous cross-sectional and follow-up investigations. … As a result, cannabinoids from cannabis may be viewed as an interesting avenue for research on obesity and associated conditions.”
Observational trial data published in 2013 in the American Journal of Medicine reported that subjects who consumed cannabis possessed favorable indices related to diabetic control compared to those without a history of recent marijuana use. Separate observational trial data published in 2012 in the British Medical Journal reported that marijuana users had a lower prevalence of type 2 diabetes and possessed a lower risk of contracting the disease than did those with no history of cannabis consumption, even after researchers adjusted for social variables such as subjects’ ethnicity, family history, and levels of physical activity.
Cross-sectional data published in 2011 in the American Journal of Epidemiology similarly reported that the prevalence of obesity in the general population is sharply lower among marijuana consumers than it is among nonusers.