Israeli investigators intend to evaluate the potential anti-tumoral effects of the canabinoid cannabidiol (CBD) in select cancer patients.
Researchers at the Hassadah Medical Center in Jerusalem will conduct a Phase II clinical trial to assess the impact of CBD as single treatment in cancer patients who have failed to respond to conventional therapies. Participants in the trial will receive CBD therapy for a period of eight weeks.
Data documenting the potent anti-cancer activity of various cannabinoids – including THC, CBD, and CBG – both in culture and in animals dates back to the mid-1970s. To date, however, virtually no clinical trials exist reproducing these results in human subjects.
In August, pharmaceutical provider Insys Therapeutics announced that it had received orphan drug status for its proprietary formulation of CBD for the treatment of glioblastoma, a hard-to-treat, aggressive form of brain cancer.
Organic CBD remains classified under federal law as a schedule I controlled substance.
Further details of the forthcoming Israeli trial are available online from the clinicaltrials.gov website here. Patient recruitment has yet to begin for this study.
In what may be the most difficult ballot initiative to evaluate in advance of the upcoming mid-term elections, the voters in Alaska will decide on November 4 whether to approve full marijuana legalization for all adults, including retail sales.
For most of us, Alaska, the largest state in the Union by area, and the least densely populated, is an exotic location, far removed from the Lower 48 both geographically and culturally. The largest city, Anchorage, has a population of only 292,000, and the second largest, Fairbanks, has only 32,000 residents. The Alaska territory was purchased from Russia in 1867 and only became a state in 1959. The state has always leaned heavily Republican, which might suggest it would be an unlikely state for marijuana legalization to appear on the ballot; but the state is also known as the home of a lot of people who want to minimize the role of government in their lives, which would appear to bode well for legalizers.
History of Marijuana Legalization in Alaska
To read the balance of this article, go to
“Rep. O’Rourke is an ardent supporter of reforming our nation’s marijuana policies,” stated NORML PAC Manager Erik Altieri, “In just his first term, he has proven to be an intelligent and pragmatic politician with a long future in front of him. We strongly encourage voters to support his re-election campaign to keep a true reform champion in Congress.”
Representative O’Rourke issued the following statement to supporters and voters on the topic:
“Those of us who live in this region, in El Paso and Juarez, have a unique perspective on the war on drugs. We know that billions of dollars in cash, drugs, guns and arms are transited through this community. We know that billions of dollars in federal resources from the United States and Mexico are spent on law enforcement to try and stop that illicit drug trade. And we also know, all too well, the suffering that accompanies that black market trade in illegal drugs. It is because of that experience and looking back over the 40-year, failed war on drugs that I’ve come to the conclusion that at least when it comes to a drug like marijuana, we owe ourselves, and especially our kids, a much better policy.
As a rational and humane country, we can decide, as we did with alcohol that the harms in the prohibition of marijuana far outweigh any gains in security and in our efforts to keep these drugs away from our fellow citizens.
If you support my work and advocacy on this issue, I hope I can count on your help.”
For the next 24 hours, Rep. O’Rourke will be running a “Powered by People” campaign with the goal of raising $123,200 in amounts less than $200 to illustrate that everyday citizens can compete with special interests in politics and issues such as marijuana law reform drive voter engagement. If you are interested in donating to this campaign you can do so by clicking here (donations are tracked so donations made through this link will show as support for his marijuana reform stance).
Traumatic brain injury (TBI) patients with a history of cannabis use possess increased survival rates compared to non-users, according data published this month in the scientific journal The American Surgeon.
UCLA Medical Center investigators conducted a three-year retrospective review of brain trauma patients. Data from 446 separate cases of similarly injured patients was assessed. Of those patients who tested positive for the presence of marijuana, 97.6 percent survived surgery. By contrast, patients who tested negative for the presence of pot prior to surgery possessed only an 88.5 percent survival rate.
“[O]ur data suggest an important link between the presence of a positive THC screen and improved survival after TBI,” the authors concluded. “This finding has support in previous literature because the neuroprotective effects of cannabinoids have been implicated in a variety of neurodegenerative diseases such as Alzheimer’s disease, Huntington’s disease, and multiple sclerosis. … With continued research, more information will be uncovered regarding the therapeutic potential of THC, and further therapeutic interventions may be established.”
The abstract of the study, “Effect of marijuana use on outcomes in traumatic brain injury,” appears online here.
As we approach the midterm elections on November 4th, I want to focus on the two statewide voter initiatives that seek to fully legalize marijuana in Alaska and Oregon. This week I will examine the proposal in Oregon, known as Measure 91.
Will the Third Time Be the Charm?
This will be the third time – and, hopefully, the charm time – that Oregon voters have voted on a marijuana legalization proposal. The first initiative, Measure 5 in 1986, the Oregon Marijuana Legalization for Personal Use Act, would have legalized the personal possession and cultivation of marijuana for personal use; it won the support of only 26 percent of the voters. More recently, Measure 80 in 2012, the Oregon Cannabis Tax Act, would have allowed the personal cultivation of marijuana and established a licensing system for the commercial production and sale of marijuana; it came close, with the support of 46.5 percent of the voters.
The latest Oregon initiative, Measure 91, proposed by New Approach Oregon, would legalize the use of marijuana by those 21 and older, and establish a system of licensing, taxing and regulating marijuana under the auspices of the Oregon Liquor Control Board.
Specifically, under this proposal adults would be permitted to possess up to eight ounces of “dried” marijuana and cultivate up to four plants. And they would be allowed to give up to an ounce of marijuana, 16 ounces of marijuana products in solid form or 72 ounces of marijuana products in liquid form, to other individuals 21 and older; they could not be compensated or reimbursed for these transactions. Adults would be allowed to purchase up to an ounce of marijuana, 16 ounces of marijuana products in solid form, or 72 ounces of marijuana products in liquid form from properly registered businesses. These limits are more permissive than those previously approved in Washington and Colorado, and may provide a test of how restrictive a legalization system must be to win the approval of a majority of the voters.