Cannabis inhalation is associated with spontaneous brain tumor regression in two subjects, according to a pair of case reports to be published in Child’s Nervous System, the official journal of the International Society for Pediatric Neurosurgery.

Investigators at the British Columbia Children’s Hospital in Vancouver documented the mitigation of residual tumors in two adolescent subjects who regularly inhaled cannabis. Authors determined that both subjects experienced a “clear regression” of their residual brain tumors over a three-year-period.

“Neither patient received any conventional adjuvant treatment” during this time period, investigators wrote. “The tumors regressed over the same period of time that cannabis was consumed via inhalation, raising the possibility that cannabis played a role in tumor regression.”

Researchers concluded, “Further research may be appropriate to elucidate the increasingly recognized effect of cannabis/cannabinoids on gliomas (brain cancers).”

A 2006 pilot study published in the British Journal of Cancer previously reported that the intratumoral administration of the cannabinoid THC was associated with reduced tumor cell proliferation in two of nine human subjects with brain cancer.

Separate preclinical studies assessing the anticancer activity of cannabinoids and endocannabinoids indicate that the substances can inhibit the proliferation of various types of cancerous cells, including breast carcinoma, prostate carcinoma, and lung cancer.

Commenting on the two new case reports, researcher Jahan Marcu — who has previously documented the inhibitory effects of cannabinoids on human glioblastoma cell proliferation and survival — wrote in the blog Freedom Is Green: “Can marijuana contribute to the regression or remission of certain cancers? Given the slow progress of clinical trials for whole plant Cannabis, it can be frustrating waiting for years, even decades, trying to answer these vital questions. But for the two young women with brain cancer in (this) report, a shift to a cannabis lifestyle may have made a difference.”

Today, the good folks at HuffingtonPost.com published my latest essay on the subject, “What Your Government Knows About Cannabis And Cancer — And Isn’t Telling You.”

Since the Huffington Post is an online medium, I made it a point to include nearly a dozen links to pertinent research and clinical/pre-clinical trials demonstrating that cannabinoids possess anti-cancer properties.

Fortunately, in the past 10 years scientists overseas have generously picked up where U.S. researchers so abruptly left off, reporting that cannabinoids can halt the spread of numerous cancer cells — including prostate cancer, breast cancer, lung cancer, pancreatic cancer, and brain cancer. (An excellent paper summarizing much of this research, “Cannabinoids for Cancer Treatment: Progress and Promise,” appears in the January 2008 edition of the journal Cancer Research.) A 2006 patient trial published in the British Journal of Cancer even reported that the intracranial administration of THC was associated with reduced tumor cell proliferation in humans with advanced glioblastoma.

For most visitors to the Huffington Post, my essay will be their first exposure to this information, but ideally, not their last. Hopefully, readers of the site — which is one of the most visited on the Internet — will join us in our calls to end the US government’s multi-decade long denial of this potentially groundbreaking research.

You can read the full text of my essay here.

Please feel free to leave a comment and/or circulate this article widely (Digg it, reddit, buzz up, etc.) My last Huff Post essay, “Don’t Buy The ‘Potent Pot’ Hype,” received nearly 100 comments, a personal response from the Drug Czar’s office, and earned me a guest spot on Dr. Drew Pinsky’s live nationally syndicated radio show. That said, in my opinion, the government’s cover-up of pot’s anti-cancer abilities is a far more important topic; hopefully we can get a similar buzz started.

PS: Those interested in learning more about this topic can download an audio file of my recent guest appearance on the radio show, “Sex, Drugs, and Civil Liberties,” (KOPN: Columbia, Missouri) here.