Study: Marijuana Use Associated With Decreased Symptoms Of Opiate Withdrawal In Methadone Maintenance Treatment SubjectsJuly 16, 2013
Cannabis consumption is associated with mitigated symptoms of opiate withdrawal in subjects undergoing methadone maintenance treatment, according to the findings of a new study published online in The American Journal on Addictions.
Investigators at the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia assessed the use of cannabis in 91 opiate-dependent subjects undergoing methadone maintenance treatment. Researchers found that subjects seeking methadone treatment who acknowledged a history of cannabis use reported “significantly less daily expenditure on acquisition of opiates.”
Authors additionally reported that subjects’ use of cannabis during treatment was associated with less severe symptoms of withdrawal on the clinical opiate withdrawal scale (COWS), an index designed to serve as an objective measure of opiate withdrawal. “[I]ncreased cannabis use was found to be associated with lower severity of [opiate] withdrawal in a subset of the sample with available chart data,” authors wrote. “These results suggested a potential role for cannabis in the reduction of withdrawal severity during methadone induction.”
They concluded, “The present findings may point to novel interventions to be employed during treatment for opiate dependence that specifically target cannabinoid–opioid system interactions.”
A 2009 study published in the same journal previously reported that moderate cannabis use and improved retention in naltrexone treatment among opiate-dependent subjects.
Full text of the study, “Impact of cannabis use during stabilization on methadone maintenance treatment,” appears online in The American Journal on Addictions.
Three quarters of medical cannabis consumers report using it as a substitute for prescription drugs, alcohol, or some other illicit substance, according to survey data published in the journal Addiction Research and Theory.
An international team of investigators from Canada and the United States assessed the subjective impact of marijuana on the use of licit and illicit substances via self-report in a cohort of 404 medical cannabis patients recruited from four dispensaries in British Columbia, Canada.
Researchers reported that subjects frequently substituted cannabis for other substances, including conventional pharmaceuticals. Authors reported:
“Over 41 percent state that they use cannabis as a substitute for alcohol (n=158), 36.1 percent use cannabis as a substitute for illicit substances (n=137), and 67.8 percent use cannabis as a substitute for prescription drugs (n=259). The three main reasons cited for cannabis-related substitution are ‘less withdrawal’ (67.7 percent), ‘fewer side-effects’ (60.4 percent), and ‘better symptom management’ suggesting that many patients may have already identified cannabis as an effective and potentially safer adjunct or alternative to their prescription drug regimen.”
Overall, 75.5 percent (n=305) of respondents said that they substitute cannabis for at least one other substance. Men were more likely than women to report substituting cannabis for alcohol or illicit drugs.
Authors concluded: “While some studies have found that a small percentage of the general population that uses cannabis may develop a dependence on this substance, a growing body of research on cannabis-related substitution suggests that for many patients cannabis is not only an effective medicine, but also a potential exit drug to problematic substance use. Given the credible biological, social and psychological mechanisms behind these results, and the associated potential to decrease personal suffering and the personal and social costs associated with addiction, further research appears to be justified on both economic and ethical grounds. Clinical trials with those who have had poor outcomes with conventional psychological or pharmacological addiction therapies could be a good starting point to further our under- standing of cannabis-based substitution effect.”
Previous studies have similarly demonstrated cannabis’ potential efficacy as an exit drug. A 2010 study published in the Harm Reduction Journal reported that cannabis-using adults enrolled in substance abuse treatment programs fared equally or better than nonusers in various outcome categories, including treatment completion. A 2009 study reported that 40 percent of subjects attending a California medical cannabis dispensary reported using marijuana as a substitute for alcohol, and 26 percent used it to replace their former use of more potent illegal drugs. A separate 2009 study published in the American Journal on Addictions reported that moderate cannabis use and improved retention in naltrexone treatment among opiate-dependent subjects in a New York state inpatient detoxification program.
Full text of the study, “Cannabis as a substitute for alcohol and other drugs: A dispensary-based survey of substitution effect in Canadian medical cannabis patients,” appears online in Addiction Research and Theory. NORML Advisory Board Member Mitch Earleywine is a co-author of this study.
As 50% of Americans now support marijuana legalization, the prohibitionists are coming out in full force with hysterical propaganda to once again terrorize voters about cannabis. We intended to scour multiple sources to compile the five most common scare tactics they use, but Joseph Summerill, director of the Summerill Group LLC, a Washington, D.C.- based law enforcement think tank and general counsel for the Major County Sheriffs’ Association, made our job easy by using all five in one op-ed piece published today in the Washington Examiner entitled, “Facts on medical marijuana are stubborn things, too“.
Lie #1) Marijuana’s not really medical. The government says so!
[M]arijuana is a Schedule I drug… a high potential for abuse or dependency… no accepted medical value… unsafe to use, even under medical supervision. [M]arijuana has not passed the rigid scrutiny of medicine proposed by the FDA.
- National Institutes of Drug Abuse (NIDA) puts the lifetime dependence rate on cannabis at 9%, same as caffeine. Alcohol has a 15% rate of abuse and Tobacco’s is 32%.
- One third of federal jurisdictions (16 states and DC) accept the medical value of cannabis.
- The federal government is supplying four Americans with this “unsafe” medicine with no medical supervision.
- Cannabis has been used medically for 5,000 years without a single human death – a far greater safety standard than an FDA that approved phen-fen and Vioxx.
For decades opponents of marijuana law reform policies have falsely argued that marijuana is a ‘gateway’ to drug abuse — a guilt-by-association charge that implies that because tens of millions of people have used cannabis and a minority of these tens of millions have also tried other drugs that somehow it must have been the pot that triggered the hard drug use.
But while reformers have been consistent — and accurate — to point out that the so-called ‘gateway theory’ lacks any statistical support (for example, the U.S. government contends that more than four in ten Americans have used cannabis, yet fewer than two percent have ever tried heroin), few in our movement have publicized the fact that for many people cannabis can be a powerful ‘exit drug’ for those looking to curb or cease their use of alcohol, opiates, or narcotics. For instance:
A 2010 study published in the Harm Reduction Journal demonstrating that cannabis-using adults enrolled in substance abuse treatment programs fared equally or better than nonusers in various outcome categories, including treatment completion.
A 2009 survey published in the Harm Reduction Journal finding that 40 percent of respondents said used marijuana as a substitute for alcohol, and 26 percent used it to replace their former use of more potent illegal drugs.
A 2009 study published in the American Journal on Addictions reporting that moderate cannabis use and improved retention in naltrexone treatment among opiate-dependent subjects in a New York state inpatient detoxification program.
A 2009 preclinical study published in the journal Neuropsychopharmacology demonstrating that oral THC suppressed sensitivity to opiate dependence and conditioning.
Based on this and other emerging evidence, investigators at the Harborside Health Center in Oakland, California are now enrolling residents in twelve-step-like classes that use cannabis to quit heroin, pills, cigarettes, alcohol, and other potentially addictive substances.
Oaklanders Quitting Oxycontin with Cannabis
via The East Bay Express
For years, there have been anecdotal reports about people using cannabis to quit harder drugs. The process is called “substitution”, and it’s a tactic that’s beginning to be endorsed by the “harm reduction” philosophy of mental health.
… So Harborside crafted a program that’s similar to traditional twelve-step programs, but ignores the pot smoking.
… Janichek is tracking the outcomes of Harborside’s free, cannabis-positive mental health services, with the goal of extrapolating the data into guidelines and replicating the services in other dispensaries.
It will be interesting to see the results of this program in the coming months — as well as the response (read: outcry) from the traditional drug treatment community.
One can expect that Harborside’s findings will further undermine the notion that cannabis is an alleged ‘gateway’ to hard drug use, and strengthen the argument that the plant may, in fact, be a useful tool for deterring the initiation or continuation of drug abuse.
Apparently my latest missive has hit a nerve — as it has quickly risen to become the most read story on Alternet.
5 Things the Corporate Media Don’t Want You to Know About Cannabis
1. Marijuana Use Is Not Associated With a Rise in Incidences of Schizophrenia
2. Marijuana Smoke Doesn’t Damage the Lungs Like Tobacco
3. Cannabis Use Potentially Protects, Rather Than Harms, the Brain
4. Marijuana Is a Terminus, Not a ‘Gateway,’ to Hard Drug Use
5. Government’s Anti-Pot Ads Encourage, Rather Than Discourage, Marijuana Use
Read the full text of the story here.