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Posts Tagged ‘Marinol’

Does the Marijuana Pill Work?

Tuesday, August 4th, 2009

This informative article from CBS News about the government’s claim that there is no need for medical patients to access cannabis, when there is a ‘fake’ cannabis pill on the market, features remarks from NORML advisory board member, professor and author

Mitch Earleywine, and former deputy drug czar under Bush 1.0 Herb Kleber, which strongly underlines the differences between credible and not credible on the topic of cannabis.

Credible:

[One] problem with Marinol is that it’s orally administered,” Dr. Mitch Earleywine, an associate professor of Clinical Psychology at the State University of New York at Albany, said in an email. “Therefore, it takes longer to work than cannabis inhaled from a vaporizer. (Usually 90 minutes at best rather than 15 seconds – a meaningful amount of time to the nauseated.)”

“It’s harder to control dosage, too, so folks end up discombobulated or without symptom relief,” he added. “In addition, folks who are vomiting can’t hold down the pills.” Earleywine also said that a dose Marinol costs three to five times as much as a comparable dose of medical marijuana.

Not Credible:

“Are there actions in the whole plant that you don’t get from just the Marinol? I would be surprised if there wasn’t,” he continued. “The problem is that most of the data about the potential medical actions of the smoked form are anecdotal.”

Dr. Kleber, who said he has prescribed Marinol to a patient and found it to be effective, points to what he characterizes as a significant advantage of the pill over traditional marijuana: “People don’t abuse it.”

“Marijuana addiction is becoming common and as a result I’m seeing an increasing number of people who have trouble stopping marijuana,” he said. “Contrary to popular beliefs that there is no marijuana withdrawal, there is marijuana withdrawal. It’s very clear cut.”

Talk about anecdotal! Dr. Kleber would have readers believe, that cannabis today, as compared to the prior 2,000 years of documented cannabis use by humans is that “Marijuana addiction is becoming common”.

Really?

“I’m seeing an increasing number of people who have trouble stopping marijuana”

Of course you are Herb because as it has been well documented by NORML that the criminal justice system throughout most of the United States presents minor cannabis offenders with the Hobson’s Choice of either going to jail or to visit the offices of the ‘Dr. Klebers’ in America for ‘treatment’.

Dr. Kleber well knows this, so his statement is for me the working definition of disingenuous!

Lastly, there is nothing new about Marinol as it has been legal and available for medical patients since the mid 1980s. If the pill worked as Dr. Kleber claims, voters and legislators in the 13 states with medical cannabis laws would not have opted for a whole plant solution.

Marinol was supposed to be the government’s great ’silver bullet’ back in the mid 1980s to end the public debate about patients’ need for whole-smoked cannabis–an analog of one of the plant’s major ingredients isolated in pill form.

Want to know more about ‘pot’ pills vs. the real thing? Checkout NORML’s published paper ‘Marinol vs. Natural Cannabis‘.

Does the Pot Pill Work?
The Government Says a Pill Called Marinol Offers the Same Benefits as
Medical Marijuana. Is it True?

By Brian Montopoli
August 4, 2009

(CBS) “Medical marijuana,” the U.S. Drug Enforcement Administration says, “already exists.”

They don’t just mean in California. A pill known as Marinol has been legal and approved by the Food and Drug Administration for use with a prescription anywhere in America since 1985.

It’s active ingredient? Dronabinol, better known as THC, the primary psychoactive element of the cannabis plant.

“Marinol provides standardized THC concentrations, does not contain the other 400 uncharacterized substances found in smoked marijuana, such as carcinogens or fungal spores, and is not associated with the quick high of smoked marijuana,” said Neil Hirsch, a spokesman for Marinol manufacturer Solvay Pharmaceuticals.

But Marinol is not the same thing as traditional, smokable marijuana. It is a less complex substance lacking both some of the good components found in traditional marijuana (such as cannabidiol, which has been found to have anti-seizure effects) and the bad or not-yet-fully-understood components (among them potential carcinogens) that can also come with the drug.

Ken Trainer, a 60-year-old Massachusetts resident who has battled Multiple Sclerosis for 25 years, said he has long been smoking marijuana to deal with the regular tremors he gets in his arms and legs.

“If I smoke a joint, the tremors go away most times before the joint is gone,” he said. “It makes my life a little easier.” Marinol, by contrast, “didn’t really do much of anything for me,” he said.

56-year-old Des Moines resident Jeff Elton, who was diagnosed with gastroparesis six years ago, had a similar experience when he was prescribed Marinol to deal with his chronic nausea and vomiting.

“I felt no relief, I didn’t feel ill, I felt nothing,” he said. “It might as well be M&M’s.”

Elton said he switched to marijuana, which he smokes through a vaporizer – a device that heats the active ingredients into a vapor instead of burning them. He said it allows him to keep down his food and regain some of the weight he lost while on Marinol.

Full Story

68 comments so far

Labs Testing For Marijuana Use By Marinol Patients

Wednesday, December 24th, 2008

By Dale Gieringer, Ph.D, Director, California NORML

California NORML has recently heard increasing reports that Marinol patients are being drug tested and denied employment for use of marijuana. In particular, we have heard from legal Prop. 215 patients who were denied jobs despite presenting Marinol prescriptions after being re-tested specifically for marijuana. Until recently, Marinol and marijuana were indistinguishable on the standard drug tests, so that patients with a Marinol prescription had a valid medical excuse under federal law for testing positive for marijuana.

However, special testing techniques have been developed that make it possible to distinguish the two by testing for non-standard cannabinoids that appear in marijuana but not Marinol. Until recently, these tests were expensive and rarely used except in high-profile criminal cases. However, it appears that they are now being routinely used by certain laboratories in cases where Marinol use is claimed. In particular, we have heard reports of such testing being used to disqualify Marinol-using Prop 215 patients by the transportation industry and by Walmart.

California NORML has accordingly altered its drug testing information to warn against relying on Marinol RXs as a screen for marijuana use: http://www.canorml.org/healthfacts/testing.tips.html

There is of course no valid scientific or health justification for allowing patients to use Marinol but not marijuana. The only purpose is to enforce compliance with the law. It is a tribute to the power and influence of the drug testing industry that they have prevailed in foisting the costs of this unnecessary and obnoxious procedure on employers.

California NORML, 2215-R Market St. #278, San Francisco CA 94114

(415) 563-5858 / www.canorml.org

22 comments so far

Yet Another Study Reports That Pot May Halt MRSA

Tuesday, September 9th, 2008

Just days after the New York Times, Scientific American, and other MSM outlets finally got wind that cannabis’ germ-fighting properties can halt the spread of MRSA and other multi-drug resistant pathogens, along comes a second just-released study identifying several new non-cannabinoid compounds in the plant which possess anti-bacterial properties.

Investigators at the University of Mississippi report the discovery of eleven new non-cannabinoid constituents in cannabis, several of which possess “anti-microbial” (think MRSA), “anti-malarial,” and “anti-leishmanial” (a common skin parasite) activity. Scientists also reported that several of the compounds also possessed anti-inflammatory properties and acted as potent anti-oxidants.

(The US government, Depart of Health and Human Services actually holds a patent on the use of certain cannabinoids as anti-oxidants and neuroprotectants, which you can read here.)

In other words, when we speak about the healing powers of the cannabis plant, we really mean the entire cannabis plant. We’re not talking about isolating particular cannabinoids, and we’re most certainly not suggesting patients be forced to consume an oral synthetic version of a single compound a la Marinol.

Therapeutic cannabis means just that — the therapeutic prowess of the whole plant. We should not advocate for, or accept, anything less.

31 comments so far

Why I’m Not Convinced Big Pharma Is Behind Pot Prohibition (But That’s Not To Say They Aren’t Looking To Cash In On Medical Marijuana)

Tuesday, July 8th, 2008

REMINDER: NORML podcaster Russ Belville and I will be discussing this essay, as well as my previous blog post “US Government Patents Medical Pot,” later today on the NORML Daily Audio Stash. An abbreviated version of my essay appears on Alternet.org here.

The US government’s longstanding denial of medical marijuana research and use is an irrational and morally bankrupt public policy. On this point, few Americans disagree. As for the question of “why” federal officials maintain this inflexible and inhumane policy, well that’s another story.

One of the more popular theories seeking to explain the Feds’ seemingly inexplicable ban on medical pot — and the use of cannabis by adults in general — goes like this: Neither the US government nor the pharmaceutical industry will allow for the use of medical marijuana because they can’t patent it or profit from it. A related, yet equally common hypothesis argues: Big Pharma lobbies the federal government to keep pot illegal because it won’t be able to compete with patients growing their own medicine.

They’re appealing theories, yet I’ve found neither to be accurate nor persuasive. Here’s why.

Full Story

19 comments so far

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